How can panel layout and composition contribute to the feeling of dread in a horror comic strip?

Asymmetrical panel layouts can create a sense of imbalance and unease. Using long, narrow panels can emphasize a character's isolation or a slow, creeping threat. Dutch angles (tilted perspectives) can convey disorientation. Empty space within panels can suggest something unseen lurking just outside the frame. Overlapping panels can create a claustrophobic effect.