How do American comics and Japanese manga typically differ in their target demographics and prevalent genres?

While both mediums cater to diverse audiences, American comics historically focused on superheroes and younger male readers, though this has diversified significantly. Japanese manga has explicitly defined target demographics (e.g., Shonen for boys, Shojo for girls, Seinen for adult men, Josei for adult women, Kodomomuke for children), leading to a broader and more explicitly categorized range of genres and themes from romance and slice-of-life to fantasy, horror, and sports.